成員介紹 » 副校長

蔡輔仁 副校長

副校長 蔡輔仁 教授

副校長 蔡輔仁 教授

聯絡資訊

 

現職

  • 中國醫藥大學 中醫學院 / 中醫學系教授
  • 中國醫藥大學　特聘教授
  • 中國醫藥大學 副校長
  • 衛生福利部 罕見疾病及藥物審議委員會 / 藥物小組 / 醫療小組委員
  • 中華民國人類遺傳學會理事
  • 中國醫藥大學附設醫院 基因醫學部主任
  • 中國醫藥大學附設醫院 遺傳中心主任
  • 中國醫藥大學附設醫院 醫學研究部主任
  • 中國醫藥大學附設醫院 兒童醫學中心醫學遺傳科主治醫師

 

學歷

年度 學歷
1993/9-1997/6 中國醫藥大學中國醫學研究所博士

 

經歷

年度 經歷
2002/3-2005/3 中華民國人類遺傳學會理事長
2003/10-2009/10 中國醫藥大學中醫學院院長
2011/1-2013/12 行政院國科會生物處內科學門二 召集人
2009/8-2015/8 中國醫藥大學研發長

 

榮譽

年度 榮譽
2002 以罕見疾病的篩檢、診斷與治療獲2002年國家生技醫療品質”品質金獎”
2004 行政院衛生署辦理之第三屆”罕見疾病藥物供應製造及研究發展”傑出貢獻獎 “
2014 中國醫藥大學學術類傑出校友

 

研究領域

  • 醫學遺傳學
  • 分子生物學
  • 兒科學

 

目前進行中研究之相關發表

“Kawasaki disease”Related Publications
  1. Lin YJ, Chang JS, Liu X, Tsang H, Chien WK, Chen JH, Hsieh HY, Hsueh KC, Shiao YT, Li JP, Lin CW, Lai CH, Wu JY, Chen CH, Lin JG, Lin TH, Liao CC, Huang SM, Lan YC, Ho TJ, Liang WM, Yeh YC, Lin JC, Tsai FJ*.　Genetic variants in PLCB4/PLCB1 as susceptibility loci for coronary artery aneurysm formation in Kawasaki disease in Han Chinese in Taiwan. 　Sci Rep. 2015 Oct 5; 5: 14762.
  2. Ko TM, Kuo HC, Chang JS, Chen SP, Liu YM, Chen HW, Tsai FJ, Lee YC, Chen CH, Wu JY, Chen YT. CXCL10/IP-10 is a biomarker and mediator for Kawasaki disease. Circ Res. 2015 Feb 27;116(5):876-83.
  3. Lin YJ, Liu X, Chang JS, Chien WK, Chen JH, Tsang H, Hung CH, Lin TH, Huang SM, Liao CC, Lin CW, Ho TJ, Tsai FJ*. Coronary artery aneurysms occurrence risk analysis between Kawasaki disease and LRP1B gene in Taiwanese children. Biomedicine (Taipei). 2014;4:10. Epub 2014 Aug 2.
  4. Lin YJ, Chang JS, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Chien WK, Chen JH, Wu JY, Chen CH, Chang LC, Lin CW, Ho TJ, Tsai FJ*.  Genetic variants of glutamate receptor gene family in Taiwanese Kawasaki disease children with coronary artery aneurysms. Cell Biosci. 2014 Nov 19;4(1):67.
  5. Lin YJ, Lan YC, Lai CH, Lin TH, Huang SM, Liao CC, Lin CW, Hung CH, Tien N, Liu X, Chien WK, Chen JH, Tsai FJ*.  Association of promoter genetic variants in interleukin-10 and Kawasaki disease with coronary artery aneurysms. J Clin Lab Anal. 2014 Nov;28(6):461-4.
  6. Chen YT, Liao WL, Lin YJ, Chen SY, Tsai FJ*.  Association between SRC-1 gene polymorphisms and coronary artery aneurysms formation in Taiwanese children with Kawasaki disease. J Clin Lab Anal. 2014 Nov;28(6):435-9.
  7. Lee YC, Kuo HC, Chang JS, Chang LY, Huang LM, Chen MR, Liang CD, Chi H, Huang FY, Lee ML, Huang YC, Hwang B, Chiu NC, Hwang KP, Lee PC, Chang LC, Liu YM, Chen YJ, Chen CH; Taiwan Pediatric ID Alliance, Chen YT, Tsai FJ*, Wu JY. Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis. Nat Genet. 2012 Mar 25;44(5):522-5.
  8. Khor CC, Davila S, Breunis WB, Lee YC, Shimizu C, Wright VJ, Yeung RS, Tan DE, Sim KS, Wang JJ, Wong TY, Pang J, Mitchell P, Cimaz R, Dahdah N, Cheung YF, Huang GY, Yang W, Park IS, Lee JK, Wu JY, Levin M, Burns JC, Burgner D, Kuijpers TW, Hibberd ML; Hong Kong–Shanghai Kawasaki Disease Genetics Consortium, Lau YL, Zhang J, Ma XJ, Liu F, Wu L; Korean Kawasaki Disease Genetics Consortium, Yoo JJ, Hong SJ, Kim KJ, Kim JJ, Park YM, Hong YM, Sohn S, Jang GY, Ha KS, Nam HK, Byeon JH, Yun SW, Han MK, Lee KY, Hwang JY, Rhim JW, Song MS, Lee HD, Kim DS, Lee JM; Taiwan Kawasaki Disease Genetics Consortium, Chang JS, Tsai FJ, Liang CD, Chen MR, Chi H, Chiu NC, Huang FY, Chang LY, Huang LM, Kuo HC, Huang KP, Lee ML, Hwang B, Huang YC, Lee PC; International Kawasaki Disease Genetics Consortium, Odam M, Christiansen FT, Witt C, Goldwater P, Curtis N, Palasanthiran P, Ziegler J, Nissen M, Nourse C, Kuipers IM, Ottenkamp JJ, Geissler J, Biezeveld M, Tacke C, Filippini L, Brogan P, Klein N, Shah V, Dillon M, Booy R, Shingadia D, Bose A, Mukasa T, Tulloh R, Michie C; US Kawasaki Disease Genetics Consortium, Newburger JW, Baker AL, Rowley AH, Shulman ST, Mason W, Takahashi M, Melish ME, Tremoulet AH; Blue Mountains Eye Study, Viswanathan A, Rochtchina E, Attia J, Scott R, Holliday E, Harrap S. Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease. Nat Genet. 2011 Nov 13;43(12):1241-6.
  9. Lin YJ, Chang JS, Liu X, Hung CH, Lin TH, Huang SM, Jeang KT, Chen CY, Liao CC, Lin CW, Lai CH, Tien N, Lan YC, Ho MW, Chien WK, Chen JH, Huang YC, Tsang H, Wu JY, Chen CH, Chang LC, Tsai FJ*. Association between GRIN3A Gene Polymorphism in Kawasaki Disease and Coronary Artery Aneurysms in Taiwanese Children. PLoS One. 2013 Nov 22;8(11):e81384.
  10. Lin YJ, Chang JS, Liu X, Lin TH, Huang SM, Liao CC, Lin CW, Chien WK, Chen JH, Wu JY, Chen CH, Chang LC, Tsang H, Jeang KT, Chen CY, Tsai FJ*. Sorting nexin 24 genetic variation associates with coronary artery aneurysm severity in Kawasaki disease patients. Cell & Bioscience 2013, 3:44.
  11. Tsai FJ, Lee YC, Chang JS, Huang LM, Huang FY, Chiu NC, Chen MR, Chi H, Lee YJ, Chang LC, Liu YM, Wang HH, Chen CH, Chen YT, Wu JY. Identification of novel susceptibility Loci for kawasaki disease in a Han chinese population by a genome-wide association study. PLoS One. 2011 Feb 4;6(2):e16853.
  12. Lin YJ, Wan L, Wu JY, Sheu JJ, Lin CW, Lan YC, Lai CH, Hung CH, Tsai Y, Tsai CH, Lin TH, Lin JG, Hsueh KC, Huang YM, Chang JS, Tsai FJ*.HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. Arthritis Rheum. 2009; 60(2):604-10.
  13. Chang CJ, Kuo HC, Chang JS, Lee JK, Tsai FJ, Khor CC, Chang LC, Chen SP, Ko TM, Liu YM, Chen YJ, Hong YM, Jang GY, Hibberd ML, Kuijpers T, Burgner D, Levin M, Burns JC, Davila S; International Kawasaki Disease Genetics Consortium; Korean Kawasaki Disease Genetics Consortium; Taiwan Kawasaki Disease Genetics Consortium, Chen YT, Chen CH, Wu JY, Lee YC. Replication and meta-analysis of GWAS identified susceptibility loci in kawasaki disease confirm the importance of B lymphoid tyrosine kinase (BLK) in disease susceptibility. PLoS One. 2013 Aug 30;8(8):e72037.  
  14. Hsieh YY, Chang CC, Hsu CM, Chen SY, Lin WH, Tsai FJ*. Major histocompatibility complex class I chain-related gene polymorphisms: associated with susceptibility to Kawasaki disease and coronary artery aneurysms. Genet Test Mol Biomarkers. 2011 Nov;15(11):755-63.
  15. Hsieh YY, Lin YJ, Chang CC, Chen DY, Hsu CM, Lo MM, Hsu KH, Tsai FJ*.  Human lymphocyte antigen B-associated transcript 2, 3, and 5 polymorphisms and haplotypes are associated with susceptibility of Kawasaki disease and coronary artery aneurysm. J Clin Lab Anal. 2010; 24(4):262-8.
  16. Huang YC, Lin YJ, Chang JS, Chen SY, Wan L, Sheu JJ, Lai CH, Lin CW, Liu SP, Chen CP, Tsai FJ*.  Single nucleotide polymorphism rs2229634 in the ITPR3 gene is associated with the risk of developing coronary artery aneurysm in children with Kawasaki disease.  Int J Immunogenet. 2010; 37(6):439-43.
  17. Sheu JJ, Lin YJ, Chang JS, Wan L, Chen SY, Huang YC, Chan C, Chiu IW, Tsai FJ*.  Association of COL11A2 polymorphism with susceptibility to Kawasaki disease and development of coronary artery lesions.  Int J Immunogenet. 2010; 37(6):487-92.
  18. Hsueh KC, Lin YJ, Chang JS, Wan L, Tsai FJ*.  BTNL2 gene polymorphisms may be associated with susceptibility to Kawasaki disease and formation of coronary artery lesions in Taiwanese children.  Eur J Pediatr. 2010; 169(6):713-9.
  19. Hsueh KC, Lin YJ, Chang JS, Wan L, Tsai YH, Tsai CH, Chen CP, Tsai FJ*. Association of interleukin-10 A-592C polymorphism in Taiwanese children with Kawasaki disease.  J Korean Med Sci. 2009; 24(3):438-42. 
  20. Chen SY, Wan L, Huang YC, Sheu JJ, Lan YC, Lai CH, Lin CW, Chang JS, Tsai Y, Liu SP, Lin YJ, Tsai FJ*.  Interleukin-18 gene 105A/C genetic polymorphism is associated with the susceptibility of Kawasaki disease.  J Clin Lab Anal. 2009; 23(2):71-6.
  21. Hsueh KC, Lin YJ, Chang JS, Wan L, Tsai YH, Tsai CH, Tsai FJ*.  Influence of interleukin 18 promoter polymorphisms in susceptibility to Kawasaki disease in Taiwan.  J Rheumatol. 2008; 35(7):1408-13.
  22. Hsueh KC, Lin YJ, Chang JS, Wan L, Tsai YH, Tsai CH, Chen CP, Tsai FJ*.Association of vascular endothelial growth factor C-634 g polymorphism in taiwanese children with Kawasaki disease.    Pediatr Cardiol. 2008; 29(2):292-6.
  23. Wu SF, Chang JS, Wan L, Tsai CH, Tsai FJ*. Association of IL-1Ra gene polymorphism, but no association of IL-1beta and IL-4 gene polymorphisms, with Kawasaki disease. J Clin Lab Anal. 2005;19(3):99-102.
  24. Wu SF, Chang JS, Peng CT, Shi YR, Tsai FJ*. Polymorphism of angiotensin-1 converting enzyme gene and Kawasaki disease. Pediatr Cardiol. 2004 Sep-Oct;25(5):529-33.
  25. “Wilson disease” Related Publications
  26. Wan L, Tsai CH, Hsu CM, Huang CC, Yang CC, Liao CC, Wu CC, Hsu YA, Lee CC, Liu SC, Lin WD, Tsai FJ*.  Mutation analysis and characterization of alternative splice variants of the Wilson disease gene ATP7B.  Hepatology. 2010; 52: 1662-70.
  27. Lin CW, Er TK, Tsai FJ, Liu TC, Shin PY, Chang JG.  Development of a high-resolution melting method for the screening of Wilson disease-related ATP7B gene mutations.  Clin Chim Acta. 2010; 6; 411(17-18):1223-31.
  28. Wan L, Tsai CH, Tsai Y, Hsu CM, Lee CC, Tsai FJ*.  Mutation analysis of Taiwanese Wilson disease patients. Biochem Biophys Res Commun. 2006; 30; 345(2):734-8.
  29. Lin CW, Er TK, Tsai FJ, Liu TC, Shin PY, Chang JG. Development of a high-resolution melting method for the screening of Wilson disease-related ATP7B gene mutations. Clin Chim Acta. 2010 Sep 6;411(17-18):1223-31.
  30. Lee CC, Wu JY, Tsai FJ, Kodama H, Abe T, Yang CF, Tsai CH. Molecular analysis of Wilson disease in Taiwan: identification of one novel mutation and evidence of haplotype-mutation association. J Hum Genet. 2000;45(5):275-9.
  31. Tsai CH, Tsai FJ, Wu JY, Chang JG, Lee CC, Lin SP, Yang CF, Jong YJ, Lo MC. Mutation analysis of Wilson disease in Taiwan and description of six new mutations. Hum Mutat. 1998;12(6):370-6.
  32. “Type 2 diabetes” related publications
  33. Lu CC, Chen YT, Chen SY, Hsu YM, Lin CC, Tsao JW, Juan YN, Yang JS, Tsai FJ.
  34. Hematopoietically expressed homeobox gene is associated with type 2 diabetes in KK Cg-Ay/J mice and a Taiwanese Han Chinese population. Exp Ther Med. 2018 Jul;16(1):185-191.
  35. Huang YC, Liao WL, Lin JM, Chen CC, Liu SP, Chen SY, Lin YN, Lei YJ, Liu HT, Chen YJ, Tsai FJ*. High levels of circulating endothelial progenitor cells in patients with diabetic retinopathy are positively associated with ARHGAP22 expression. Oncotarget. 2018 Apr 3;9(25):17858-17866.
  36. Tsai FJ, Li TM, Ko CH, Cheng CF, Ho TJ, Liu X, Tsang H, Lin TH, Liao CC, Li JP, Huang SM, Lin JC, Lin CC, Liang WM, Lin YJ.  Effects of Chinese herbal medicines on the occurrence of diabetic retinopathy in type 2 diabetes patients and protection of ARPE-19 retina cells by inhibiting oxidative stress. Oncotarget. 2017 Jun 29;8(38):63528-63550.
  37. Yang JS, Lu CC, Kuo SC, Hsu YM, Tsai SC, Chen SY, Chen YT, Lin YJ, Huang YC, Chen CJ, Lin WD, Liao WL, Lin WY, Liu YH, Sheu JC, Tsai FJ*. Autophagy and its link to type II diabetes mellitus. Biomedicine (Taipei). 2017 Jun;7(2):8. doi: 10.1051/bmdcn/2017070201. Epub 2017 Jun 14.
  38. Chiang HL, Wang NH, Song IW, Chang CP, Wen MS, Chien YH, Hwu WL, Tsai FJ, Chen YT, Wu JY. Genetic epidemiological study doesn't support GLA IVS4+919G>A variant is a significant mutation in Fabry disease. Mol Genet Metab. 2017 May;121(1):22-27.
  39. Tsai FJ, Ho TJ, Cheng CF, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JG, Lin JC, Lin CC, Liang WM, Lin YJ. Effect of Chinese herbal medicine on stroke patients with type 2 diabetes. J Ethnopharmacol. 2017 Mar 22;200:31-44.
  40. Liao WL, Lee WJ, Chen CC, Lu CH, Chen CH, Chou YC, Lee IT, Sheu WH, Wu JY, Yang CF, Wang CH, Tsai FJ*.  Pharmacogenetics of dipeptidyl peptidase 4 inhibitors in a Taiwanese population with type 2 diabetes.  Oncotarget. 2017 Mar 14;8(11):18050-18058.
  41. Tsai FJ, Ho TJ, Cheng CF, Shiao YT, Chien WK, Chen JH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JG, Lan YC, Liu YH, Hung CH, Lin JC, Lin CC, Lai CH, Liang WM, Lin YJ.  Characteristics of Chinese herbal medicine usage in ischemic heart disease patients among type 2 diabetes and their protection against hydrogen peroxide-mediated apoptosis in H9C2 cardiomyoblasts. Oncotarget. 2017 Feb 28;8(9):15470-15489.
  42. Huang KC, Li TM, Liu X, Chen JH, Chien WK, Shiao YT, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Lin JC, Lin CC, Lai CH, Cheng CF, Liang WM, Hung CH, Chen CC, Lin YJ, Tsai FJ*.  KCNQ1 variants associate with hypertension in type 2 diabetes and affect smooth muscle contractility in vitro.  J Cell Physiol. 2017 Dec;232(12):3309-3316.
  43. Chen YT, Liao JW, Tsai YC, Tsai FJ*.  Inhibition of DNA methyltransferase 1 increases nuclear receptor subfamily 4 group A member 1 expression and decreases blood glucose in type 2 diabetes.  Oncotarget. 2016 Jun 28;7(26):39162-39170.
  44. Chen SY, Hsu YM, Lin YJ, Huang YC, Chen CJ, Lin WD, Liao WL, Chen YT, Lin WY, Liu YH, Yang JS, Sheu JC, Tsai FJ*.  Current concepts regarding developmental mechanisms in diabetic retinopathy in Taiwan.  Biomedicine (Taipei). 2016 Jun;6(2):7.
  45. Lin YJ, Ho TJ, Yeh YC, Cheng CF, Shiao YT, Wang CB, Chien WK, Chen JH, Liu X, Tsang H, Lin TH, Liao CC, Huang SM, Li JP, Lin CW, Pang HY, Lin JG, Lan YC, Liu YH, Chen SY, Tsai FJ* , Liang WM.  Chinese Herbal Medicine Treatment Improves the Overall Survival Rate of Individuals with Hypertension among Type 2 Diabetes Patients and Modulates In Vitro Smooth Muscle Cell Contractility.  PLoS One. 2015 Dec 23;10(12):e0145109.
  46. Huang KC, Huang HJ, Chen CC, Chang CT, Wang TY, Chen RH, Chen YC, Tsai FJ*.  Susceptible gene of stasis-stagnation constitution from genome-wide association study related to cardiovascular disturbance and possible regulated traditional Chinese medicine. BMC Complement Altern Med. 2015 Jul 14;15:229.
  47. Chen YT, Lin WD, Liao WL, Lin YJ, Chang JG, Tsai FJ*.  PTPRD silencing by DNA hypermethylation decreases insulin receptor signaling and leads to type 2 diabetes.  Oncotarget. 2015 May 30;6(15):12997-3005.
  48. Liao WL, Tsai FJ*.  Personalized medicine in Type 2 Diabetes. Biomedicine (Taipei). 2014;4:8. Epub 2014 Aug 6.
  49. Liao LN, Chen CC, Wu FY, Lin CC, Hsiao JH, Chang CT, Kardia SL, Li TC, Tsai FJ*.  Identified single-nucleotide polymorphisms and haplotypes at 16q22.1 increase diabetic nephropathy risk in Han Chinese population.  BMC Genet. 2014 Oct 31;15:113.
  50. Chen M, Lin WR, Lu CH, Chen CC, Huang YC, Liao WL, Tsai FJ*.  Chimerin 2 genetic polymorphisms are associated with non-proliferative diabetic retinopathy in Taiwanese type 2 diabetic patients.  J Diabetes Complications. 2014 Jul-Aug;28(4):460-3. S
  51. Huang KC, Chen CC, Su YC, Lin JS, Chang CT, Wang TY, Chen RH, Tsai FJ*.
  52. The Relationship between Stasis-Stagnation Constitution and Peripheral Arterial Disease in Patients with Type 2 Diabetes.  Evid Based Complement Alternat Med. 2014;2014:903798.
  53. Lin HJ, Huang YC, Lin JM, Liao WL, Wu JY, Chen CH, Chou YC, Chen LA, Lin CJ, Tsai FJ*. Novel susceptibility genes associated with diabetic cataract in a Taiwanese population. Ophthalmic Genet. 2012 Nov 9.
  54. DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet. 2014 Feb 9. doi: 10.1038/ng.2897.
  55. Lin HJ, Huang YC, Lin JM, Wu JY, Chen LA, Tsai FJ*. Association of Genes on Chromosome 6, GRIK2 , TMEM217 and TMEM63B (Linked to MRPL14) with Diabetic Retinopathy. Ophthalmologica. 2012 Sep 28.
  56. Li H, Gan W, Lu L, Dong X, Han X, Hu C, Yang Z, Sun L, Bao W, Li P, He M, Sun L, Wang Y, Zhu J, Ning Q, Tang Y, Zhang R, Wen J, Wang D, Zhu X, Guo K, Zuo X, Guo X, Yang H, Zhou X; DIAGRAM Consortium; AGEN-T2D Consortium, Zhang X, Qi L, Loos RJ, Hu FB, Wu T, Liu Y, Liu L, Yang Z, Hu R, Jia W, Ji L, Li Y, Lin X. A genome-wide association study identifies GRK5 and RASGRP1 as type 2 diabetes loci in Chinese Hans. Diabetes. 2013 Jan;62(1):291-8.
  57. Xi B, Takeuchi F, Chandak GR, Kato N, Pan HW; AGEN-T2D Consortium, Zhou DH, Pan HY, Mi J. Common polymorphism near the MC4R gene is associated with type 2 diabetes: data from a meta-analysis of 123,373 individuals. Diabetologia. 2012 Oct;55(10):2660-6.
  58. Hsieh YY, Huang YC, Chang CC, Wang YK, Lin WH, Tsai FJ*. Chromosome 15q21-22-related polymorphisms and haplotypes are associated with susceptibility to type-2 diabetic nonproliferative retinopathy. Genet Test Mol Biomarkers. 2012 May;16(5):442-8.
  59. Cho YS, Chen CH, Hu C, Long J, Ong RT, Sim X, Takeuchi F, Wu Y, Go MJ, Yamauchi T, Chang YC, Kwak SH, Ma RC, Yamamoto K, Adair LS, Aung T, Cai Q, Chang LC, Chen YT, Gao Y, Hu FB, Kim HL, Kim S, Kim YJ, Lee JJ, Lee NR, Li Y, Liu JJ, Lu W, Nakamura J, Nakashima E, Ng DP, Tay WT, Tsai FJ, Wong TY, Yokota M, Zheng W, Zhang R, Wang C, So WY, Ohnaka K, Ikegami H, Hara K, Cho YM, Cho NH, Chang TJ, Bao Y, Hedman ÅK, Morris AP, McCarthy MI; DIAGRAM Consortium; MuTHER Consortium, Takayanagi R, Park KS, Jia W, Chuang LM, Chan JC, Maeda S, Kadowaki T, Lee JY, Wu JY, Teo YY, Tai ES, Shu XO, Mohlke KL, Kato N, Han BG, Seielstad M. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians. Nat Genet. 2011 Dec 11;44(1):67-72.
  60. Liao WL, Chen CC, Chang CT, Wu JY, Chen CH, Huang YC, Tsai CH, Tsai FJ*. Gene polymorphisms of adiponectin and leptin receptor are associated with early onset of type 2 diabetes mellitus in the Taiwanese population. Int J Obes (Lond). 2012 Jun;36(6):790-6.
  61. Huang YC, Lin JM, Lin HJ, Chen CC, Chen SY, Tsai CH, Tsai FJ*. Genome-wide association study for diabetic retinopathy in a Taiwanese population. Ophthalmology. 2011 Apr;118(4):642-8.
  62. Tsai FJ, Yang CF, Chen CC, Chuang LM, Lu CH, Chang CT, Wang TY, Chen RH, Shiu CF, Liu YM, Chang CC, Chen P, Chen CH, Fann CS, Chen YT, Wu JY.  A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese. PLoS Genet. 2010; 6(2):e1000847.
  63. Lin HJ, Huang YC, Lin JM, Wu JY, Chen LA, Lin CJ, Tsui YP, Chen CP, Tsai FJ*.  Single-nucleotide polymorphisms in chromosome 3p14.1- 3p14.2 are associated with susceptibility of Type 2 diabetes with cataract. Mol Vis. 2010; 16:1206-14.
  64. Kuo WW, Chung LC, Liu CT, Wu SP, Kuo CH, Tsai FJ, Tsai CH, Lu MC, Huang CY, Lee SD.  Effects of insulin replacement on cardiac apoptotic and survival pathways in streptozotocin-induced diabetic rats.  Cell Biochem Funct. 2009; 27(7):479-87.
  65. Chen CC, Wu JY, Chang CT, Tsai FJ, Wang TY, Liu YM, Tsui HC, Chen RH, Chiou SC.  Levels of retinol-binding protein 4 and uric acid in patients with type 2 diabetes mellitus.  Metabolism. 2009; 58(12):1812-6.

*Corresponding author

 

著作專書

著作專書
1998 小兒完全健康手冊
2002 與基因共舞：遺傳疾病淺說

 

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