成員介紹 » 校長

江安世 校長

聯絡資訊

 

Affiliation 現職

  • 中國醫藥大學 校長
  • 教育部終身國家講座
  • 總統府中央研究院院士
  • 世界科學院院士

 

FIELDS OF SPECIALTY 專業領域

  • Brain research
  • Connectomics
  • Neurogenetics
  • Behavioral Neuroscience
  • Bioimaging

 

EDUCATION 學歷

  • 1990 Ph.D. in Entomology, Rutgers University, New Jersey, USA
  • 1983 M.S. in Plant Pathology and Entomology, National Taiwan University, Taiwan
  • 1981 B.S. in Entomology, National Chung-Hsing University, Taiwan

 

ACADEMIC POSITIONS 學術職位

ACADEMIC POSITIONS
2024-present    Adjunct Tenured Chair Professor (合聘終身講座教授), National Chiao Tung University (陽明交通大學) 
2023-present Adjunct Professor (合聘教授), Institute of Life Sciences, National Defense Medical Center (國防醫學院) 
2021-present Adjunct Distinguished Chair Professor (合聘特聘講座教授), Institute of Brain and Mind Sciences, National Taiwan University (台灣大學)
2019-present Adjunct Chair Professor (合聘講座教授), Tunghai University (東海大學)
2017-present Adjunct Investigator (合聘研究員), Institute of Molecular and Genomic Medicine, The National Health Research Institutes (國家衛生院) 
2016-present Adjunct Investigator (合聘研究員), Institute of Physics, Academia Sinica (中央研究院)
2016-present Adjunct Distinguished Investigator (合聘特聘研究員), National Synchrotron Radiation Research Center (國家同步輻射研究中心)
2016-present Adjunct Distinguished Chair Professor (合聘特聘講座教授), Graduate Institute of Clinical Medical Science, China Medical University (中國醫藥大學) 
2014-present Adjunct Chair Professor (合聘講座教授), Kaohsiung Medical University (高雄醫學大學講座教授)
2014-present Tsing Hua Distinguished Chair Professor (特聘講座教授), National Tsing Hua University (清華大學)
2014-2020 Dean, College of Life Science, National Tsing Hua University, Taiwan
2013-present Scientific Advisory Board member (兼任科學顧問), Center for Brain Activity Mapping at UCSD
2013-2015 Scientific Advisory Board member (兼任科學顧問), Cold Spring Harbor Conferences Asia, China
2011-2024 International Faculty (合聘國際研究員), Kavli Institute for Brain and Mind at the University of California, San Diego, USA. (美國聖地牙哥Kavli腦與心智研究中心)
2010-2023 Adjunct Chair Professor, National Chiao Tung University (陽明交通大學)
2008-present Adjunct Investigator (合聘研究員), Genomics Research Center, Academia Sinica (中央研究院)
2007-2014 Tsing Hua Chair Professor, National Tsing Hua University
2006-2008 Adjunct Professor (合聘教授), Cold Spring Harbor Laboratory, USA (美國冷泉港實驗室)
2005 Chair of Biological Science Panel, National Science Council
2005-2010 Adjunct Professor, Department of Life Science, National Central University
2004-present Director (兼任中心主任), Brain Research Center, National Tsing Hua University
2002-2008 Director, Institute of Biotechnology, National Tsing Hua University
2001-2002 Visiting Scientist, Cold Spring Harbor Laboratory, USA
1997 Visiting Professor, Neurobiology Laboratory, CNRS, France
1997-present Professor, Department of Life Science, National Tsing Hua University
1994-2005 Advisor of EM Center, National Tsing Hua University
1992-1997 Associate Professor, Department of Life Science, National Tsing Hua University
1990-1992 Postdoc, Rutgers University, New Jersey, USA

 

HONOR 榮譽

Awards and Honors
2024, 2019      清華大學產學合作績優教師
2022 Honorary Doctorate of Kaohsiung Medical University (高雄醫學大學 榮譽博士)
2022, 21, 20, 18  「FUTURE TECH Award」National Science and Technology Council (國科會「未來科技獎」4次)
2021     National Chair Professorship Award, Ministry of Education (教育部第24屆終身國家講座，生物及醫農類科) 
2020 Memorial Lecture of Li Yih-Yuen Emeritus Chair Professor (李亦園院士榮譽講座)
2020 Hou-De Honorary Chair (厚德榮譽講座)
2017 「遠見」雜誌再度選為「新台灣之光100」
2016 TWAS Fellow (世界科學院 院士) 
2016 Presidential Special Lecturer, The Society for Neuroscience 2016 Annual Meeting (>35,000 participants)
2015 National Chair Professorship Award, Ministry of Education (教育部第19屆國家講座，生物及醫農類科) 
2014 Academician, Academia Sinica (中央研究院 院士)
2013 有庠科技獎-科技論文獎
2012 Published the first Taiwanese’s "Science" full article
2012 AEARU Distinghuished Lecture (東亞研究型大學協會傑出講座)
2012 TWAS Prize in Biologoy (世界科學院 生物學類獎)
2012 Hou Jindui Distinguished Honor Award (侯金堆傑出榮譽獎—基礎科學生物類)
2011-2013 Academic Summit Project, NSC (國科會攻頂計畫)
2010 「遠見」雜誌-選為中華民國建國百年「新台灣之光100」
2009 The Fifty Scientific Achievements, NSC 50th anniversary (國科會50週年慶「50科學成就」)
2008 Teco Award of Teco Technology Foundation (東元科技獎化工/生物/醫工領域)
2008 HuiSun Chair of National Chung Hsing University (中興大學蕙蓀講座)
2007 Distinguished Alumnus of National Chung Hsing University (中興大學傑出校友)
2007 Outstanding Scholar Award, Foundation for the Advancement of Outstanding Scholarship (傑出人才基金會傑出人才講座)
2007 Sun Yat-sen Academic Award (中山學術獎)
2007 Outstanding Contributions in Science & Technology, Executive Yuan (行政院傑出科技貢獻獎)
2007 Academic Award of Ministry of Education (教育部學術獎)
2007 Published the first Taiwanese’s "Cell" paper
200,420,102,013 Outstanding Research Award, MOST, Taiwan (科技部傑出獎三次)

 

BIO-SKETCH 個人簡歷

Dr. Ann-Shyn Chiang received his Ph.D. in 1990 and completed postdoctoral training at Rutgers University in 1992. He joined National Tsing Hua University as an Associate Professor in 1992, became a Professor in 1997, and took a sabbatical at Cold Spring Harbor Laboratory in 2001. In 2011, he became an adjunct faculty member at the Kavli Institute for Brain and Mind at UC San Diego.

Dr. Chiang is known for his pioneering connectomics research on memory. His work includes the first brain-wide wiring diagram in Drosophila, which The New York Times described as a step toward mapping the human brain. His discoveries, including the role of protein synthesis in long-term memory, were featured in Taiwan’s first full article in Science in 2012.

He has received numerous honors, including election as an Academician of Academia Sinica (2014), TWAS Prize in Biology (2012), and the National Chair Award (2015, 2020). He is currently the Director of the Brain Research Center and Distinguished Chair Professor at National Tsing Hua University.

 

MAJOR SCIENTIFIC ACHIEVEMENTS 重大科學成就

  • Odor Representation in Higher Brain Centers: Uncovered neuronal temporal identity and mechanisms for gating CO2 information, advancing understanding of olfactory processing (Cell, 2006, 2007; Science, 2013).
  • Long-Term Memory in Engram Neurons: Found that long-term memory requires protein synthesis in a small subset of neurons, essential for memory consolidation (Science, 2012; Cell Reports, 2023).
  • 3D Fly Brain Database: Developed the first brain-wide wiring map at single-neuron resolution, aiding sensory circuit mapping (Current Biology, 2011; Nature Communications, 2015).
  • Tissue Clearing Technology: Created FocusClear technology, the first tissue-clearing reagent compatible with GFP for high-resolution 3D imaging of intact brains at 30 nm resolution (Nature Communications, 2019).

 

SELLECTED PUBLICATIONS 著作

(Full list of 155 papers available upon request, *: corresponding author, IF: impact factor)

SELECTED PUBLICATIONS
  1. Cheng LS†, Charng CC†, Chen RH, Feng KL, Chiang AS*, Lo CC* and Lee TK* (2025) Hybrid neural networks in the mushroom body drive olfactory preference in Drosophila. Science Advances11, DOI: 10.1126/sciadv.adq9893 (IF: 14.136)
  2. Chu LA, Tai CY, Chiang AS* (2024) Thirst-driven hygrosensory suppression promotes water seeking in Drosophila.Proc Natl Acad Sci USA 121, e2404454121. (IF: 11.205)
  3. Chuang YH, Wu YF, Lin YH, Chen YH, Zhou YX, Hsu SC, Li SM, Chiang AS, Chen YC, Chen SJ, Lin SJ* and Chu LA* (2024) Super resolution imaging in collagen abundant thick tissues. Small Structures 2024, 2400231. (IF: 15.9)
  4. Abubaker MB, Hsu FY, Feng KL, Chu LA, de Belle JS, Chiang AS* (2024). Asymmetric neurons are necessary for olfactory learning in the Drosophila brain. Current Biology 34, 1–12. (IF: 10.834)  
  5. Chen CC*, Lin HW, Feng KL, Tseng DW, de Belle JS, Chiang AS* (2023) A subset of cholinergic mushroom body neurons blocks long-term memory formation in Drosophila. Cell Reports 42,112974. (IF: 9.995)
  6. Sakamura S, Hsu FY, Tsujita A, Abubaker MB, Chiang AS, and Matsuno K* (2023) Ecdysone signaling determines lateral polarity and remodels neurites to form Drosophila’s left-right brain asymmetry. Cell Reports 6, 112337. (IF: 9.995)
  7. Manubens-Gil L, Zhou Z, Chen H, Ramanathan A, Liu X, Liu Y, Bria A, Gillette T, Ruan Z, Yang J, Radojević M, Zhao T, Cheng L, Qu L, Liu S, Bouchard K, Gu L, Cai W, Ji S, Roysam B, Wang CW, Yu H, Sironi A, Iascone DM, Zhou J, Bas E, Sousa EC, Aguiar P, Li X, Li Y, Nanda S, Wang Y, Muresan L, Fua P, Ye B, He H, Staiger JF, Peter M, Cox DN, Simonneau M, Oberlaender M, Jefferis G, Ito K, Bellido PG, Kim J, Rubel E, Cline HT, Zeng H, Nern A, Chiang AS, Roskams J, Livesey R, Stevens J, Liu T, Dang C, Guo Y, Zhong N, Tourassi G, Hill S, Hawrylycz M, Koch C, Meijering E*, Ascoli GA*, Peng H* (2023) BigNeuron: A resource to benchmark and predict performance of algorithms for automated tracing of neurons in light microscopy datasets. Nature Methods 20, 824–835. (IF: 47.99)
  8. Stampfl APJ, Liu Z, Hu J, Sawada K, Takano H, Kohmura Y, Ishikawa T, Lim JH, Je JH, Low CM, Teo A, Tok ES, Tan TW, Ban K, Libedinsky C, Tan FCK, Chen KP, Yang AC, Chuang CC, Chen NY, Shih CT, Lee TK, Yang DN, Lai HC, Shuai HH, Cheng CC, Ching YT, Li CW, Charng CC, Lo CC, Chiang AS, Recur B, Petibois C, Cheng CL, Chen HH, Yang SM, Hwu Y, Rojviriya C, Rugmai S, Rujirawat S, Margaritondo G* (2023) SYNAPSE: An international roadmap to large brain imaging. Physics Reports999, 1–60. (IF: 25.6) [DOI]
  9. Lin HW#, Chen CC#*, Jhang RY, Chen L, de Belle JS, Tully T, Chiang AS* (2022) CREBB repression of protein synthesis in mushroom body gates long-term memory formation in Drosophila. Proc Natl Acad Sci USA 119, e2211308119. (IF: 11.205) [DOI]
  10. Lin HW#, Chen CC#, de Belle JS, Tully T*, Chiang AS* (2021) CREBA and CREBB in two identified neurons gate long-term memory formation in Drosophila. Proc Natl Acad Sci USA 118, e2100624118. (IF: 11.205) [DOI]
  11. Chu LA#, Lu CH#, Yang SM, Liu YT, Feng KL, Tsai YCh, Chang WK, Wang WC, Chang SW, Chen P, Lee TK, Hwu YK, Chiang AS*, Chen BC* (2019) Rapid single-wavelength lightsheet localization microscopy for clarified tissue. Nature Communications 10, 4762. (IF: 14.919) [DOI]
  12. Feng KL and Chiang AS* (2019) Forgetting memories through distinct actin remodeling mechanisms. Proc Natl Acad Sci USA 116, 20807–20808. (IF: 11.205) [Link]
  13. Sung YC, Jin PR, Chu LA, Hsu FF, Wang MR, Chang CC, Chiou SJ, Qiu JT, Gao DY, Lin CC, Chen YS, Hsu YC, Wang J, Wang FN, Yu PL, Chiang AS, Wu Anthony YT, Ko John JS, Lai Charles PK, Lu TT*, Chen Y* (2019) Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies. Nature Nanotechnology 14, 1160-1169. (IF: 39.213)
  14. Zhang Y, Tsang TK, Bushong EA, Chu LA, Chiang AS, Ellisman MH, Reingruber J, Su CY* (2019) Asymmetric ephaptic inhibition between compartmentalized olfactory receptor neurons. Nature Communications 10, 1560. (IF: 14.919)
  15. Wu JK, Tai CY, Feng KL, Chen SL, Chen CC, Chiang AS* (2017) Long-term memory requires sequential protein synthesis in three subsets of mushroom body output neurons in Drosophila. Scientific Reports7: 7112 [DOI] (IF: 4.996)
  16. Hwu Y*, Margaritondo G* and Chiang AS* (2017) Q&A: Why use synchrotron x-ray tomography for multi-scale connectome mapping? BMC Biology15:122 [DOI] (IF: 6.779)
  17. Lo CC*, Chiang AS* (2016) Toward whole-body connectomics.J Neurosci 36, 11375–11383. (IF: 6.167) (This review article reports the synchrotron x-ray imaging approach for mapping the connectome at single-neuron resolution (Nature 2017), based on Chiang’s Presidential Lecture at the Neuroscience 2016 Annual Meeting).
  18. Shih HW, Wu CL, Chang SW, Liu TH, Lai JSY, Fu TF, Fu CC, Chiang AS* (2015) Parallel circuits control temperature preference in Drosophila during aging. Nature Communications 6, 7775. (IF: 14.919)
  19. Shih CT*, Sporns O, Yuan SL, Su TS, Lin YJ, Chuang CC, Wang TY, Lo CC, Greenspan RJ, Chiang AS* (2015) Connectomics-based analysis of information flow in the Drosophila brain. Current Biology 25, 1249-1258. (IF: 10.834)
  20. Schoofs A, Hückesfeld S, Schlegel P, Miroschnikow A, Bader R, Zeymer M, Spieß R, Chiang AS, Pankratz MJ* (2014) Selection of motor programs for suppressing food intake and inducing locomotion in the Drosophila brain. PLoS Biol 12, e1001893. (IF: 9.593)
  21. Wu MC, Chu LA, Hsiao PY, Lin YY, Chi CC, Liu TH, Fu CC*, Chiang AS* (2014) Optogenetic control of selective neural activity in multiple freely moving Drosophila adults. Proc Natl Acad Sci USA 111, 5367-5372. (IF: 11.205)
  22. Wu CL, Shih MF M, Lee PT, Chiang AS* (2013) An octopamine–mushroom body circuit modulates the formation of anesthesia-resistant memory in Drosophila. Current Biology 23, 1-9. (IF: 10.834)
  23. Lin HH, Chu LA, Fu TF, Dickson BJ, Chiang AS* (2013) Parallel neural pathways mediate CO2 avoidance responses in Drosophila. Science 340, 1338-1341. (IF: 47.728 ; this article has been reviewed in the “PERSPECTIVES” of the same Science issue, p1295-1297)
  24. Lin CY, Chuang CC, Hua TE, Chen CC, Dickson BJ, Greenspan RJ, Chiang AS* (2013) A comprehensive wiring diagram of the protocerebral bridge for visual information processing in the Drosophila brain. Cell Reports 3, 1739-1753. (IF: 9.995)
  25. Pai TP, Chen CC, Lin HH, Chin AL, Lai JSY, Lee PT, Tully T, Chiang AS* (2013) Drosophila ORB protein in two mushroom body-output neurons is necessary for long-term memory formation. Proc Natl Acad Sci USA 110, 7898-7903. (IF: 11.205)
  26. Lehnert BP, Baker AE, Gaudry Q, Chiang AS, Wilson RI* (2013) Distinct roles of TRP channels in auditory transduction and amplification in Drosophila. Neuron 77, 115-128. (IF: 15.982)
  27. Chen CC, Wu JK, Lin HW, Pai TP, Fu TF, Wu CL, Tully T, Chiang AS* (2012) Visualizing long-term memory formation in two neurons of the Drosophila brain. Science 335, 678–685. [101年大學指考試題39-41] (IF: 47.728; This article was reviewed in the “PERSPECTIVES” of the same Science issue, p664-665; this article has been introduced by the Science Editor in the “EDITOR’S CHOICE” of the Science Signaling 14, ec50). This is the first Science full article published by Taiwanese scientists.
  28. Lai JSY, Lo SJ, Dickson BJ and Chiang AS* (2012) Auditory circuit in the Drosophila brain. Proc Natl Acad Sci USA 109, 2607-2612. (IF: 11.205)
  29. Chiang AS* (2011) Q&A: Ann-Shyn Chiang. Current Biology 21, R938-R939. (IF: 10.834)
  30. Lee PT, Lin HW, Chang YH, Fu TF, Dubnau J, Hirsh J, Lee T and Chiang AS* (2011) Serotonin-mushroom body circuit modulating the formation of anesthesia-resistant memory in Drosophila. Proc Natl Acad Sci USA 108, 13794–13799. (IF: 11.205)
  31. Wu CL, Shih MF Lai SY, Yang HT, Turner GC, Chen L, Chiang AS* (2011) Heterotypic gap junctions between two neurons in the Drosophila brain are critical for memory. Current Biology 21, 848-854. (IF: 10.834)
  32. Chiang AS*, Lin CY, Chuang CC, Chang HM, Hsieh CH, Yeh CW, Shih CT, Wu JJ, Wang GT, Chen YC, Wu CC, Chen GY, Ching YT, Lee PC, Lin CY, Lin HH, Wu CC, Hsu HW, Huang YA, Chen JY, Chiang HJ, Lu CF, Ni RF, Yeh CY, Hwang JK (2011) Three-dimensional reconstruction of brainwide wiring networks in Drosophila at single cell resolution. Current Biology 21, 1-11. (Article, cover story, [DOI], IF: 10.834; The New York Times reported this as the first step toward decoding the human brain  [DOI])
  33. Wu CL, Xia S, Fu TF, Wang H, Chen YH, Leong D, Chiang AS*, Tully T* (2007) Specific requirement of NMDA receptors for long-term memory consolidation in Drosophila ellipsoid body. Nature Neuroscience 10, 1578-1586. (IF: 24.884)
  34. Lin HH, Lai JSY, Chin AL, Chen YC, Chiang AS* (2007) A map of olfactory representation in the Drosophila mushroom body. Cell 128, 1205-1218. (IF: 41.582). This is the first Cell paper published by Taiwanese scientists.
  35. Zhu S, Lin S, Kao CF, Awasaki T, Chiang AS, Lee T* (2006) Gradients of the Drosophila chinmo BTB-zinc finger protein govern neuronal temporal identity. Cell 127, 409-422. (IF: 41.582)
  36. Xia S, Miyashita T, Fu TF, Lin WY, Wu CL, Pyzocha L, Lin IR, Saitoe M, Tully T, Chiang AS* (2005) NMDA receptors mediate olfactory learning and memory in Drosophila. Current Biology 15, 603-615. (IF: 10.834; this article has been reviewed in the “Dispatch” of the Current Biology 15, R414-R419)
  37. Agrawal N, Pallos J, Slepko N, Apostol BL, Bodai L, Chang LW, Chiang AS, Thompson LM, Marsh JL (2005) Identification of combinatorial drug regimens for treatment of Huntington’s disease using Drosophila. Proc Natl Acad Sci USA 102, 3777-3781. (IF: 11.205)
  38. Iijima K, Liu HP, Chiang AS, Konsolaki M, Zhong Y* (2004) Dissecting the pathological effects of human Abeta40 and Abeta42 in Drosophila: a potential model for Alzheimer's disease. Proc Natl Acad Sci USA 101, 6623-6628. (IF: 9.809)
  39. Tamura T, Chiang AS, Ito N, Liu HP, Horiuchi J, Tully T, Saitoe M* (2003) Aging specifically impairs amnesiac-dependent memory in Drosophila. Neuron 40, 1003-1011. (IF: 15.982)
  40. Dubnau J, Chiang AS, Grady L, Barditch J, Gossweiler S, McNeil J, Smith P, Buldoc F, Scott R, Certa U, Broger C, Tully T* (2003) The staufen/pumilio pathway is involved in Drosophila long-term memory. Current Biology 13, 286-296. (cover story) (IF: 10.834; this article has been reviewed in the “Dispatch” of the Current Biology13, R126-R127)
  41. Wang Y, Chiang AS, Xia S, Kitamoto T, Tully T, Zhong Y* (2003) Blockade of neurotransmission in Drosophila mushroom bodies impairs odor attraction but not repulsion. Current Biology 13, 1900-1904. (IF: 10.834)
  42. Chiang AS*, Lin WY, Liu HP, Pszczolkowski MA, Fu TF, Chiu SL, Holbrook GL (2002) Insect NMDA receptors mediate juvenile hormone biosynthesis. Proc Natl Acad Sci USA 99, 37-42. (IF: 11.205)

 

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