成員介紹 » 副校長

趙坤山 副校長

副校長 趙坤山 教授

副校長 趙坤山 教授

聯絡資訊

 

現職

  • 中國醫藥大學 副校長
  • 中國醫藥大學附設醫院 生醫產業籌備處 處長
  • 中國醫藥大學附設醫院 癌症中心 院長

 

學歷

年度 學歷
1982 高雄醫學大學 醫學系 醫學士

 

經歷

年度 經歷
2008/5-2015 Professor and Chair, Department of Radiation Oncology, Columbia University College of Physicians and Surgeons
2008/5-2014 Residency Program Director, Radiation Oncology Columbia University College of Physicians and Surgeons
2008/5-2015 Professor and Chief, Division of Radiation Oncology, Weill Cornell College of Medicine
2008/5-2015 Director of Combined Radiation Oncology Program at New York Presbyterian Hospital-Columbia University Medical Center- Weill Cornell College of Medicine
2002/6-2008/4 Director of Image-guided Therapy, Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston TX
1998/7-2002/4 Barnes-Jewish Hospital, Cancer Center Committee, St. Louis, MO
1999/7-2002/4 Washington University Medical Center, Human Studies Committee, Internal Review Board, St.Louis, MO
1998/7-2002/4 Barnes-Jewish Hospital, Associate Director of Residency Training Program, St. Louis, MO
1988/7-2002/4 Barnes-Jewish Hospital, Cancer Center, Education Subcommittee, St. Louis, MO
2001/6-2002/5 President, North America Taiwanese Medical Association, St. Louis, MO
1999/7-2001/4 Chair, Membership Committee, North America Taiwanese Professor Association, St. Louis, MO

 

研究領域

  • 癌症放射治療
  • 癌症分子影像診斷及治療
  • 各項特殊癌症治療技術

 

榮譽

榮譽
Best Doctors in America, 2004-2005, 2005-2006, 2007-2008, 2008-2009, 2009-2010, 2011-2012,2012-2013, 2013-2014.
America’s Top Doctors, Castle Connolly Medical – New Yorker Magazine, 2012, 2013, 2014.
Taiwanese American Citizen League (TACL) and Taiwanese American Professionals (TAP) Life Time Achievement Award, 2012.
Chu H. Chang Distinguished Professor, Columbia University College of Physicians and Surgeons, 2008.
Keynote Speaker of 2014 Second Chinese World Congress of Radiological Sciences, Suzhou, China.
Keynote Speaker of 2009 Asian Pacific Head and Neck Oncology Congress, Taipei, Taiwan, September 18, 2009
Keynote Speaker of 2008 International Symposium on Cancer Nanotechnology and Image-guidedTherapy, Taipei, Taiwan, December 25, 2008
Keynote Speaker of 2006 Taiwan Radiology Society meeting, Kaohsiung, Taiwan, March 26, 2006.
Keynote Speaker of 2006 International Society of Gastroenterology Oncology ICACT/ISGIO meeting, Paris, France, February 1, 2006
Annual Oration in Radiation Oncology, Radiological Society of North America (RSNA) Chicago, Illinois, November 30, 2005.
Keynote Speaker of 8th Japan 3-D CRT Symposium, Ciba, Japan, July 25, 2003.
Richard Evan Memorial Lecture at University of Kansas. February 14, 2003.
ASTRO/ESTRO Travel Award Oct. 1997.
Essay Award - Gilbert H. Fletcher Society, Nineteenth Annual Meeting of the Gilbert H. Fletcher Society, Houston, Texas, April 7-9, 1994.
Essay Award - American Brachytherapy Society, Sixteenth Annual Meeting of the American Brachytherapy Society, Scottsdale, Arizona December 8-11, 1993.
Best Intern of the Year, Chang-Gung Memorial Hospital, 1982
President, Medical Student Association, Kaohsiung Medical School, 1981
Head, Aboriginal Area Medical Service Corporation, Kaohsiung Medical School, 1980

 

著作目錄 [ 2011~2015 ]

SELECTED PUBLICATIONS
Jinxue He, Xi Kang, Yuxin Yin, K. S. Clifford Chao & Wen H. Shen, PTEN regulates DNA replication progression and stalled fork recovery. Nature Commun. 2015; 6:7620
Wang TJ, Saad S, Qureshi YH, Jani A, Isaacson SR, Sisti MB, Bruce JN, McKhann GM 2nd, Lesser J, Cheng SK, Clifford Chao KS, Lassman AB. Outcomes of gamma knife radiosurgery, bi-modality & tri-modality treatment regimens for patients with one or multiple brain metastases: the Columbia University Medical Center experience. J Neurooncol. 2015 Apr;122(2):399-408. doi: 10.1007/s11060-015-1728-y. Epub 2015 Feb 17.
Singh P, Desai P, Arora S, Pham AH, Wernicke AG, Smith M, Nori D, Clifford Chao KS, Parashar B. Comparison of primary radiation versus robotic surgery plus adjuvant radiation in high-risk prostate cancer: a single center experience. J Cancer Res Ther. 2015 Jan-Mar;11(1):191-4. doi: 10.4103/0973-1482.139601.
Ye JC, Yan W, Christos P, Nori D, Chao KS, Ravi A. Second cancer, breast cancer, and cardiac mortality in stage T1aN0 breast cancer patients with or without external beam radiation therapy: a national registry study. Clin Breast Cancer. 2015;15(1):54-59.
Nagar H, Boothe D, Ginter PS, Sison C, Vahdat L, Shin S, Smith M, Chao KS, Nori D, Hayes MK. Disease-free survival according to the use of postmastectomy radiation therapy after neoadjuvant chemotherapy. Clin Breast Cancer. 2015;15(2):128-134.
J. Manzerova, J. Chang, M. Santos Delamerced, Z. Li, D. Nori, M.A. Hayes, M.J. Smith, D.J. Brenner, K. Chao, I. Shuryak, J. Ng, Predicting Potential Radiation-Associated Cardiac Risks for Left-Breast Cancer Patients Treated With Postmastectomy or Breast and Regional Nodal Radiation Therapy, , International Journal of Radiation Oncology Biology Physics 2014;90, S266.
Wernicke AG, Yondorf MZ, Peng LK, Trichter S, Nedialkova L, Sabbas A, Kulidzhanov F, Parashar B, Nori D, Chao KSC, Christos P, Kovanlikaya I, Pannullo S, Boockvar JA, Stieg PE, Schwartz TH. Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases Clinical article. Journal of Neurosurgery. 2014;121(2):338-348.
Wernicke AG, Varma S, Greenwood EA, Christos PJ, Chao KSC, Liu H, Bander NH, Shin SJ. Prostate-specific membrane antigen expression in tumor-associated vasculature of breast cancers. Apmis. 2014;122(6):482-489.
Wang S, Li Z, Chao KS, Chang J. Calibration of a detector array through beam profile reconstruction with error-locking. J Appl Clin Med Phys. 2014;15(6):4591.
Stessin A, Banu M, Boockvar JA, Parashar B, Wernicke AG, Nori D, Chao KSC. MAP Kinase Signaling Differences between Neural Stem Cells and Glioma Cells Provide a Mechanism for Selective Neuroprotection During Cranial Irradiation. International Journal of Radiation Oncology Biology Physics. 2014;90:S148-S148.
Peng LC, Milsom J, Garrett K, Nandakumar G, Coplowitz S, Parashar B, Nori D, Chao KSC, Wernicke AG. Surveillance, Epidemiology, and End Results-based analysis of the impact of preoperative or postoperative radiotherapy on survival outcomes for T3N0 rectal cancer. Cancer Epidemiology. 2014;38(1):73-78.
Patel SH, Ma Y, Wernicke AG, Nori D, Chao KSC, Parashar B. Evidence supporting contemporary post-operative radiation therapy (PORT) using linear accelerators in N2 lung cancer. Lung Cancer. 2014;84(2):156-160.
Nagar H, Zhou LL, Biritz B, Sison C, Chang JH, Smith M, Nori D, Chao KSC, Hayes MK. Is There a Tradeoff in Using Modified High Tangent Field Radiation for Treating an Undissected Node-Positive Axilla? Clinical Breast Cancer. 2014;14(2):109-113.
Liu SH, Chao KS, Leu YS, Lee JC, Liu CJ, Huang YC, Chang YF, Chen HW, Tsai JT, Chen YJ.Guideline and Preliminary Clinical Practice Results for Dose Specification and Target Delineation for Postoperative Radiotherapy of Oral Cavity Cancer. Head Neck. 2014 Mar 14. doi: 10.1002/hed.23692
Berry SL, Polvorosa C, Cheng S, Deutsch I, Chao KS, Wuu CS. Initial clinical experience performing patient treatment verification with an electronic portal imaging device transit dosimeter. Int J Radiat Oncol Biol Phys. 2014 Jan 1;88(1):204-9. doi: 10.1016/j.ijrobp.2013.09.045. PMID: 24210671
Wernicke, A.G., Lazow, S., Yondorf, M., Kovanlikaya, I., Nori, D., Chao KS, Christos, P., Boockvar, J., Pannullo, S., Stieg, P. and Schwartz, T.: MRI resection cavity dynamics following implantation of Cesium-131 brachytherapy in patients with brain metastases.  Journal of Neurosurgery, 2013.
Parashar B, Singh P, Christos P, Arora S, Desai P, Wernicke AG, Delamerced M,  Boothe D, Nori D, Chao KS. Stereotactic body radiation therapy (SBRT) for early stage lung cancer delivers clinically significant radiation to the draining lymph nodes. J Radiosurg SBRT. 2013;2(4):339-340. PubMed PMID: 24383044; PubMed Central PMCID: PMC3874935
Huang YC, Chao KS, Liao HF, Chen YJ. Targeting sonic hedgehog signaling by compounds and derivatives from natural products Evid Based Complement Alternat Med. 2013;2013:748587. doi: 10.1155/2013/748587. Epub 2013 May 20.PMID: 23762158
Shah A, Chao KS, Ostbye T, Castleberry AW, Pietrobon R, Gloor B, Clary BM, White RR, Worni M. Trends in racial disparities in pancreatic cancer surgery. J Gastrointest Surg. 2013 Nov;17(11):1897-906. doi: 10.1007/s11605-013-2304-4. PMID: 24002757
Wernicke AG, Varma S, Greenwood EA, Christos PJ, Chao KS, Liu H, Bander NH, Shin SJ. Prostate-specific membrane antigen expression in tumor-associated vasculature of breast cancers. APMIS. 2013 Dec 5. doi: 10.1111/apm.12195. PMID: 24304465
Boothe DL, Coplowitz S, Greenwood E, Barney CL, Christos PJ, Parashar B, Nori D, Chao KS, Wernicke AG. Transforming Growth Factor β-1 (TGF-β1) Is a Serum Biomarker of Radiation Induced Fibrosis in Patients Treated With Intracavitary Accelerated Partial Breast Irradiation: Preliminary Results of a Prospective Study. Int J Radiat Oncol Biol Phys. 2013 Dec 1;87(5): 1030-6. doi: 10.1016/j.ijrobp.2013.08.045. PMID: 24139518
Greenwood EA, Coplowitz S, Patel P, Sharma N, Kulidzhanov F, Christos PJ, Fischer A, Parashar B, Nori D, Chao KS, Wernicke AG. Assessment of pain as a sequela in patients treated with intracavitary brachytherapy accelerated partial breast irradiation (IBAPBI): preliminary results of a prospective study.Breast J. 2013 Nov-Dec;19(6):595-604. doi: 10.1111/tbj.12174. PMID:24102810
Nagar H, Boothe D, Parikh A, Yondorf M, Parashar B, Gupta D, Holcomb K, Caputo T, Chao KS, Nori D, Wernicke AG. Administration of concurrent vaginal brachytherapy during chemotherapy for treatment of endometrial cancer.Int J Radiat Oncol Biol Phys. 2013 Nov 15;87(4):665-9. doi: 10.1016/j.ijrobp.2013.08.014. PMID: 24138915
Nagar H, Zhou L, Biritz B, Sison C, Chang J, Smith M, Nori D, Chao KS, Hayes MK. Is There a Tradeoff in Using Modified High Tangent Field Radiation for Treating an Undissected Node-Positive Axilla? Clin Breast Cancer. 2013 Oct 27. pii: S1526-8209(13)00241-3. doi: 10.1016/j.clbc.2013.10.004. PMID: 24291379.
Liao HF, Chao KS, Chen YJ, Chang MS. Complementary and alternative medicine in cancer stem cells. Evid Based Complement Alternat Med. 2013;2013:560274. doi: 10.1155/2013/560274. Epub 2013 Aug 6. No abstract available. PMID: 23986783.
Huang YC, Chao KS, Liao HF, Chen YJ. Targeting sonic hedgehog signaling by compounds and derivatives from natural products Evid Based Complement Alternat Med. 2013;2013:748587. doi: 10.1155/2013/748587. Epub 2013 May 20.PMID: 23762158.
Wernicke AG, Greenwood EA, Coplowitz S, Parashar B, Kulidzhanov F, Christos PJ, Fischer A, Nori D, Chao KS. Tissue compliance meter is a more reproducible method of measuring radiation-induced fibrosis than late effects of normal tissue-subjective objective management analytical in patients treated with intracavitary brachytherapy accelerated partial breast irradiation: results of a prospective trial. Breast J. 2013 May-Jun; 19(3):250-8. PMID: 23614363.
Wang JC, Zhang C, Wei Y, Horowitz DP, Connolly EP, Cheng SK, Feng W, Chao KS, Israel Deutsch. Comparison of effect of rectal volume delineation methods on dose constraint endpoints in the treatment of prostate cancer with intensity-modulated radiation therapy.  J Radiat Oncol 24 May 2013.
Su YC, Li SC, Wu YC, Wang LM, Chao KS, Liao HF.  Resveratrol Down regulates     inInterleukin-6-Stimulated Sonic Hedgehog Signaling in Human Acute Myeloid Leukemia. Evid Based Complement Alternat Med. 2013; 2013:547430.doi: 10.1155/2013/547430. PMID:23533494.
Yan P, Cheese borough JC 3rd, Chao KS Automatic Shape-Based Level Set Segmentation for Needle Tracking in 3-D TRUS-Guided Prostate Brachytherapy. Ultrasound Med Biol. 2012 Sep;38(9):1626-36 PMID:22763006.
Parashar B, Wernicke AG, Rice S, Osborne J, Singh P, Nori D, Vallabhajosula S, Goldmith S, Chao, K.S. Early assessment of radiation response using a novel functional imaging modality – [18F]fluorocholine PET (F-PET): a pilot study. Discov Med 2012 Jul;14(74): 13-20 PMID: 22868241.
Yan W, Christos P, Nori D, Chao KS, Ravi A. Is There a Cause-specific Survival Benefit of Postmastectomy Radiation Therapy in Women Younger Than Age 50 With T3N0 Invasive Breast Cancer?  A SEER Database Analysis: Outcomes by Receptor Satus/Race/Age : Analysis Using the NCI Surveillance, Epidemiology, and End Result (SEER) Database. Am J Clin Oncol. 2012 Aug 2 PMID: 22868241.
Liao HF, Su YC, Zheng ZY, Jhih Cai C, Hou MH, Chao KS, Chen YJ. Sonic hedgehog signaling regulates Bcr-Abl expression in human chronic myeloid leukemia cells. Biomed Pharmacother. 66(5):378-83, 2012. PMID:22397755.
Li B, Chen M, Nori D, Chao KS, Chen AM, Chen SL Adjuvant Radiation Therapy and Survival for Pure Tubular Breast Carcinoma-Experience From the SEER Database. Int J Radiat Oncol Biol Phys. 2012 Sep PMID: 22543207.
Chen YJ, Kuo CD, Chen SH, Chen WJ, Huang WC, Chao KS, Liao HF Small-molecule synthetic compound norcantharidin reverses multi-drug resistance y regulating Sonic hedgehog signaling in human breast cancer cells. PLoS on. 2012 Epub 2012 May 15. PMID:22615870.
Sharma C, Deutsch I, Horowitz DP, Hershman DL, Lewin SN, Lu YS, Neugut AI, Herzog TJ, Chao KS, Wright JD. Patterns of care and treatment outcomes for elderly women with cervical cancer. 2011 Oct 28. doi: 10.1002/cncr.26589.
Sharma C, Deutsch I, Lewin SN, Burke WM, Qiao Y, Sun X, Chao KS , Herzog TJ, Wright JD. Lymphadenectomy influences the utilization of adjuvant radiation treatment for endometrial cancer. Am J Obstet Gynecol. 2011 Dec;205(6):562.e1-9.
Chen YJ, Lin CP, Hsu ML, Shieh HR, Chao NK, Chao KS. Sonic hedgehog signaling protects human hepatocellular carcinoma cells against ionizing radiation in an autocrine manner. Int J Radiat Oncol Biol Phys. 2011 Jul 1;80(3):851-9. Epub 2011 Mar 4.
Parashar B, Patel P, Singh P, Monni S, Trichter S, Sabbas A, Wernicke AG, Nori D, Chao KS. Management of Single Malignant Lung Nodules in Elderly Patients (70 Years or Older) Who are Not Candidates for Lobectomy. Am J Clin Oncol. 2011 May 6
Parashar B, Wernicke AG, Pavese A, Singh P, Trichter S, Sabbas A, Kutler DI, Kuhel W, Port JL, Lee PC, Nori D, Chao KS. Cesium-131 permanent seed brachytherapy: dosimetric evaluation and radiation exposure to surgeons, radiation oncologists, and staff. Brachytherapy 2011 Nov;10(6):508-13. doi: 10.1016/j.brachy.2011.04.002.
Patel PS, Yan W, Trichter S, Sabbas A, Rosenblatt R, Drotman MB, Swistel A, Chao KS, Nori D, Hayes MK. Seroma is an expected consequence and not a complication of MammoSite brachytherapy. Breast J. 2011 Sep-Oct;17(5):498-502. doi: 10.1111/j.1524-4741.2011.01127.x.
Wernicke AG, Goodman RL, Turner BC, Komarnicky LT, Curran WJ, Christos PJ, Khan I, Vandris K, Parashar B, Nori D, Chao KS. A 10-year follow-up of treatment outcomes in patients with early stage breast cancer and clinically negative axillary nodes treated with tangential breast irradiation following sentinel lymph node dissection or axillary clearance. Breast Cancer Res Treat. Breast Cancer Res Treat. 2011 Feb;125(3):893-902.